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Jarrow Formulas MK-7 (vitamin K2), 60 Softgels


Diabetes

Jarrow Formulas MK-7 (vitamin K2), 60 Softgels

Jarrow FORMULAS MK-7 is made via fermentation by Bacillus subtilus natto. MK-7 (Menaquinone-7) is an enhanced bioactive form of vitamin K2 from Natto that is ten times better absorbed than K1 from spinach. MK-7 is responsible for the carboxylation of specific bone proteins needed for building bone.Also, MK-7 promotes cardiovascular health by helping to maintain arterial elasticity.SUGGESTED USAGE: Take 1 softgel per day or as directed by your qualified health care consultant. NOTE: If you have a medical condition, are pregnant, lactating, trying to conceive, under the age of 18, or taking medications (especially anticoagulants [e.g. warfarin/Coumadin]), consult your health care practitioner before using this product. Keep out of the reach of children. OTHER INGREDIENTS: Medium chain triglycerides, evening primrose oil, and soybean oil. Softgel consists of gelatin, glycerin, water and caramel (as a light barrier). Contains: Soy. No wheat, no gluten, no dairy, no egg, no fish/shellfish, no peanuts/tree nuts.

Jarrow Formulas MK-7, 60 Softgels
At a Glance:
  • A superior vitamin K product
  • Offers an enhanced bioactive form of vitamin K2 from cultured Bacillus natto
  • Ten times better absorbed than K1 from spinach
  • Ideal for anyone seeking optimum cardiovascular health and healthy bones*
Jarrow Formulas MK-7, 60 Softgels Product Shot

Offers an enhanced bioactive form of vitamin K2 from cultured Bacillus natto.

Jarrow Formulas MK-7, 60 Softgels Product Shot

Ten times better absorbed than K1 from spinach. View larger.

Beyond Coagulation

The story of vitamin K began in 1929 when the Danish researcher Henrik Dam discovered its role in coagulation. Vitamin K is integral to the conversion of the amino acid glutamic acid (Glu) into gamma-carboxyglutamate (Gla). Proteins containing Gla are important in coagulation processes. These proteins work together in a complex cascade to create fibrin that strengthens platelets and helps to stop the flow of blood when necessary. Almost fifty years later, vitamin K benefits beyond coagulation were discovered.*

Vitamin K is a group name for a number of structurally related compounds including phylloquinone (vitamin K1) and menaquinones (K2 vitamins). The synthetic, short-chain vitamin K1 is commonly used in food supplements, but recently the natural, long-chain menaquinone-7 (MK-7) has also become available as a dietary supplement. All forms of vitamin K serve as a cofactor for the posttranslational carboxylation of certain protein bound glutamate residues, which are converted into gamma-carboxyglutamate (Gla). These Gla residues form calcium-binding sites that are essential for the activity of the proteins in which they are found. The most recognized Gla-containing proteins are the blood coagulation factors II, VII, IX, and X, which are all synthesized in the liver. Gla proteins not related to blood clotting are osteocalcin (synthesized in bone) and matrix Gla protein (mainly synthesized in cartilage and in the vessel wall).

For example, carboxylated matrix Gla protein binds calcium and helps guard against the deposition of calcium in arteries. Likewise, researchers have confirmed that vitamin K activates matrix Gla protein and promotes arterial health.*

Osteocalcin is the most abundant vitamin K-dependent protein in bone. It is synthesized by the bone forming cells known as osteoblasts and plays an important role in the regular deposition of hydroxyapatite in the bones. The amount of osteocalcin that is not carboxylated [under-carboxylated osteocalcin] is considered a sensitive measure of vitamin K status in bone, with an elevated percentage of under-carboxylated osteocalcin associated with low dietary intakes of vitamin K. As a result, bone health relies heavily on the activation of osteocalcin by vitamin K. Studies show that when supplemental vitamin K is given to people with inactive osteocalcin, active levels will rise.*

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Modern scientific evidence has linked low vitamin K intake with a number of suboptimal health conditions. In addition, vitamin K supplements have been shown to help maintain healthy bone density and display a beneficial effect on the elastic properties of the arterial vessel wall.*

Superiority of K2

The K2 vitamins include the menaquinones, MK-7, MK-8, and MK-9 and are present in some fermented foods, most notably natto. Natto is a traditional Japanese fermented soybean food, which is produced by growing the MK-7 generating Bacillus natto on the surface of cooked soybean. Natto also happens to be the richest dietary source of vitamin K presently known, almost all of which occurs in the form of MK-7. The longer-chain menaquinones, including MK-7, are more hydrophobic, have longer half-lives and are incorporated into low-density lipoproteins. Moreover, MK-7 from natto, or Bacillus natto fermentation, is much better absorbed than K1 from spinach. While vitamin K1 is primarily absorbed by the liver, MK-7 is absorbed in extra hepatic tissues, such as the arterial wall, pancreas, and testes.*

A recent study compared the in vivo properties of two forms of vitamin K: MK-7 and K1. Researchers demonstrated that after oral ingestion, MK-7 is more effective in catalyzing osteocalcin carboxylation in bone.* They also noted that K1 declined to its baseline level within several hours, whereas MK-7 remained detectable for at least 4 days. The longer half-life means MK-7 is available to support bone and arterial integrity for much longer periods than other forms of vitamin K.*

During the last ten years, several studies have looked at the relationship between food intake and bone health. Evidence of stronger bones in people eating natto adds weight to the theory that people generally have insufficient serum levels of vitamin K2 for optimum bone and arterial health. Furthermore, a long-term population-based study, carried out in the Netherlands between 1990 and 2000, demonstrated that dietary intake of vitamin K2, but not vitamin K1, promoted optimum cardiovascular health.*

Warning:

Do NOT use if taking anticoagulant drugs (such as Warfarin) or other medications.

About Jarrow Formulas

Jarrow Formulas’ complete line of over 350 nutritional products includes vitamins, minerals, probiotics, standardized herbal concentrates, amino acids, enzymes and enteral nutrition products. Customers can be assured of purity, value and potency when choosing these products.

What’s in the Box

Jarrow Formulas MK-7, 60 Softgels.

FDA Disclaimer

Other Products from Jarrow Formulas:

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Product Features

  • Derived from Natto
  • Promotes bone and cardiovascular health
  • Dietary supplement

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3 Comments

3 Comments

  1. Kate McMurry

    February 17, 2013 at 3:25 pm

    Crucial vitamin for heart and bone health MK-7 (Menaquinone-7) is an enhanced bioactive form of Vitamin K2 made from the soy product natto by a special process of fermentation. Research has discovered that this form of Vitamin K is far better absorbed by the body than K1, which is found in vegetables such as spinach.I personally use this brand, because Jarrow is a highly reputable company. The suggested use for this product is one softgel per day or as directed by your qualified health care provider. I personally take one of these softgels per day. It can be taken with food or on an empty stomach.MK-7 helps promote bone health by helping the body naturally–with no side effects–to build bone, which is an essential factor in preventing osteoporosis.Let me pause here to say that this supplement stands in strong contrast to Big Pharma’s “bone-protecting” drugs. They, in fact, do not build bone. The drugs doctors most often prescribe for a DEXA-based diagnosis of “osteopenia” are from a class called “antiresorptives.” These drugs attempt to slow bone loss by decreasing the rate of absorption of bone by osteoclast cells. Examples include: bisphosphonates (Fosamax, Boniva, Actonel, Reclast), calcitonin (Fortical and Miacalcin), estrogen therapy or hormone therapy (Premarin, Prempro), and estrogen agonists/antagonists (Evista). There’s a huge problem with these drugs, over and beyond their dangerous side effects. Stopping resorption works entirely against the body’s bone-maintenance system. In a natural state (untampered with by drugs), there is a constant uptake by osteoclast cells of old bone tissue (resorption) which triggers a signal to the osteoblast cells to create new bone tissue. Both sides of the equation are essential for new bone to be created. In short, if there is no resorption of old bone by osteoclasts, then the osteoblasts will NOT make any new bone. This means that if I take bisphosphonates my body stops making any new bone. My conclusion is this: Yes, during the relatively short-term testing of two years or less Big Pharma has done on these drugs, it has concluded and proclaimed that bone is spared, rather than lost. Unfortunately, due to how the body works, this type of medication cannot prevent osteoporosis over the long term. In fact, tragically, it is actually creating a form of osteoporosis, which is defined as a body filled with old, fragile bone tissue that is susceptible to breakage. Recent research has also indicated that the bisphosphonates in particular can create osteonecrosis (bone death) of the jaw and spontaneous femur fractures. There are major class-action lawsuits going forward on this health tragedy right now.Research has indicated that the bone growth that MK-7 promotes can be additionally augmented by taking it in combination with Vitamin D3. Multiple studies have demonstrated synergistic benefits when vitamin MK-7 and D3 are combined. There is enhanced osteocalcin accumulation in bone cells which leads to increased bone mineral density. Both MK-7 and Vitamin D3 encourage calcium uptake where it needs to go, to bones and teeth, not to where it should not go, the walls of your arteries.Speaking of arteries, MK-7 promotes cardiovascular health by helping to maintain arterial elasticity due to the function just described, of encouraging calcium in the body to go where it belongs, not where it does not, forming plaque in blood vessels.

  2. D. Mantelli "I am part of the Amazon Tribe kn...

    February 17, 2013 at 3:47 pm

    Vitamin K2 for your health Vitamin K2 is may help in with following:-Blood clotting-Prevention of Heart Disease and Arterial Plaque-Enhance Bone Health and Prevent Osteoporosis-Fight Cancer-Boost the Immune System and Help Prevent the Signs of Aging-May reduce the risk of type 2 diabetesVitamin K2 is best absorbed with food containing fat. The softgels are small and easy to swallow with no noticeable smell or taste.

  3. Jules Abramson

    February 17, 2013 at 3:53 pm

    Everyone should take this! “The inverse association between heart disease and vitamin K2 intake is more straightforward. In The Rotterdam Study, which prospectively followed just over 4,600 men aged 55 or older in the Netherlands, the highest intake of vitamin K2 was associated with a 52 percent lower risk of severe aortic calcification, a 41 percent lower risk of coronary heart disease (CHD), a 51 percent lower risk of CHD mortality, and a 26 percent lower risk of total mortality. Even though the study population consumed ten times more K1 than K2, vitamin K1 had no association with either the degree of aortic calcification or the risk of heart disease. The profound effects of variations in such small amounts of dietary K2 emphasize just how powerful this substance is in the prevention of degenerative disease.”From the Weston A. Price Foundation quoting Chris Masterjohn

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